Dit spel is verdeeld in 50 achievements waarvoor je een totaal van 1000 punten kan krijgen. Hieronder volgt de lijst met achievements:
| Achievement |
Omschrijving |
Punten |
| Completed Welcome |
Successfully complete the Welcome To Rapture Level. |
10 |
| Maxed One Track |
Purchased every slot in one of the Plasmid or Tonic tracks |
20 |
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| Maxed All Tracks |
Purchased every slot in all four Plasmid and Tonic tracks |
50 |
| Bought One Slot |
Purchase one slot in any Plasmid or Tonic track |
5 |
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| Upgraded a Weapon |
Acquire at least one weapon upgrade. |
5 |
| One Fully Upgraded Weapon |
Fully upgrade one weapon. |
5 |
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| Two Fully Upgraded Weapons |
Fully upgrade two weapons. |
5 |
| Three Fully Upgraded Weapons |
Fully upgrade three weapons. |
10 |
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| Four Fully Upgraded Weapons |
Fully upgrade four weapons. |
10 |
| Five Fully Upgraded Weapons |
Fully upgrade five weapons. |
10 |
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| Weapon Specialist |
Acquire all upgrades for all weapons. |
20 |
| Fully Researched Thug Splicer |
Fully research the Thuggish Splicer. |
10 |
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| Fully Researched Gun Splicer |
Fully research the Leadhead Splicer. |
10 |
| Fully Researched Spider Splicer |
Fully research the Spider Splicer. |
10 |
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| Fully Researched Houdini Splicer |
Fully research the Houdini Splicer. |
10 |
| Fully Researched Nitro Splicer |
Fully research the Nitro Splicer. |
10 |
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| Fully Researched Rosie |
Fully research the Rosie. |
10 |
| Fully Researched Bouncer |
Fully research the Bouncer. |
10 |
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| Fully Researched Little Sister |
Fully research the Little Sister. |
10 |
| Prolific Photographer |
Take at least one photo in every research group. |
5 |
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| Research PhD |
Max out all possible research. |
20 |
| Quality Research Photo |
Take a Research Photo of the highest grade. |
20 |
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| Researched a Splicer |
Take at least one Research Photo of a Splicer. |
5 |
| One Successful Hack |
Perform at least one successful hack. |
5 |
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| Hacked a Security Bot |
Successfully hack a security bot. |
10 |
| Hacked a Security Camera |
Successfully hack a security camera. |
10 |
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| Hacked a Turret |
Successfully hack a turret. |
10 |
| Hacked a Vending Machine |
Successfully hack a vending machine. |
10 |
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| Hacked a Safe |
Successfully hack a safe. |
10 |
| Skilled Hacker |
Successfully complete 50 hacks. |
40 |
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| Basic Inventor |
Successfully invent at least one item. |
5 |
| Avid Inventor |
Successfully invent at least 100 items. |
10 |
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| Ammo Inventor |
Successfully invented all possible ammo types. |
25 |
| Little Sister Savior |
Complete the game without harvesting any Little Sisters. |
100 |
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| Tonic Collector |
Collect or Invent 53 Tonics in the Physical, Engineering and Combat tracks. |
50 |
| Historian |
Find every audio diary. |
50 |
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| Seriously Good At This |
Complete the game on the hardest difficulty setting. |
40 |
| Dealt with every Little Sister |
Either Harvest or Rescue every Little Sister in the game |
40 |
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| Lucky Winner |
Hit the jackpot at a slot machine |
10 |
| Toaster in the Tub |
Shock an enemy in the water. |
10 |
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| Achievement |
Omschrijving |
Punten |
| Defeated Dr. Steinman |
The player has defeated the crazed Dr. Steinman |
15 |
| Defeated Peach Wilkins |
The player has defeated Peach Wilkins |
15 |
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| Restored the Forest |
The player has restored the forests of Arcadia |
15 |
| Completed Cohen’s Masterpiece |
The player has completed Sander Cohen’s great masterpiece |
30 |
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| Defeated Andrew Ryan |
The player has defeated Andrew Ryan |
30 |
| Broke Fontaine’s Mind Control |
The player has broken Fontaine’s mind control |
30 |
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| Defeated Atlas |
The player has defeated Atlas |
100 |
| Became a Big Daddy |
The player has become a Big Daddy. |
30 |
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| Irony |
The player has taken a picture of Sander Cohen’s corpse |
10 |
| Found Cohen’s Room |
The player has entered Sander Cohen’s personal quarters. |
10 |
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